José Alejandro Rauh-Hain, M.D.

研究概况

The IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) project is focused on hereditary cancer syndromes, such as Hereditary Breast and Ovarian Cancer (HBOC) Syndrome and Lynch Syndrome (LS). These inherited syndromes significantly elevate a person’s lifetime cancer risk, necessitating early and frequent cancer screening and sometimes risk-reducing surgeries like mastectomies. Cascade genetic testing is a powerful tool to identify those more likely to have inherited cancer syndromes and guide preventive measures.

The primary objective of this study is to engage and support a diverse population to increase the identification of people with known HBOC or LS and their at-risk relatives, while eliminating obstacles for them to access cascade genetic testing through the IGNITE-TX intervention.

IGNITE-TX aims to assist families dealing with HBOC and LS by effectively identifying and communicating with at-risk relatives, providing education about hereditary cancer syndromes and genetic testing as a pathway to cancer prevention, and offering patient navigation and creating personalized plans. Additionally, the project aims to implement systematic tracking of cascade genetic testing progress and to assess the effectiveness of IGNITE-TX through a randomized controlled trial comparing four interventions: usual care, free genetic counseling and testing, IGNITE-TX and IGNITE-TX combined with free genetic counseling and testing.

我的“为什么”

My interest in cancer research stems from a combination of clinical experience and a passion for addressing health care disparities. As a gynecologic oncologist and researcher, I have a unique perspective on the quality of care for women with cancer. I am driven to examine and reduce disparities in gynecologic cancer care through real-world research studies.

I aspire to lead a research program focused on reducing disparities in cancer care delivery, particularly in genetic testing and risk-reducing interventions for underserved populations, ultimately improving patient outcomes.

为什么资金如此重要

Funding from the Prevent Cancer Foundation is integral to the success of IGNITE-TX, our initiative focused on hereditary cancer syndromes such as Hereditary Breast and Ovarian Cancer Syndrome and Lynch Syndrome.

Funding is pivotal in turning our vision into a reality, benefiting countless people trying to stay ahead of hereditary cancers. We anticipate the most profound outcome will be saving lives by identifying high-risk individuals and guiding them toward timely interventions, thus reducing cancer-related morbidity and mortality.